4-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-2-pyrrolidinecarboxylic acid methyl ester hydrochloride
(2S,4R)-4-Boc-Aminopyrrolidine-2-carboxylic acid methyl ester hydrochloride
CAS: 913742-54-8
Molecular Formula: C11H21ClN2O4
4-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-2-pyrrolidinecarboxylic acid methyl ester hydrochloride - Names and Identifiers
4-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-2-pyrrolidinecarboxylic acid methyl ester hydrochloride - Physico-chemical Properties
| Molecular Formula | C11H21ClN2O4 |
| Molar Mass | 280.75 |
| Storage Condition | Inert atmosphere,Room Temperature |
4-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-2-pyrrolidinecarboxylic acid methyl ester hydrochloride - Introduction
(2S,4R)-Acid hydrochloride is a drug intermediate commonly used in chemical synthesis and drug development.
Nature:
Chemical name:(2S,4R)-acid methyl ester hydrochloride
Molecular formula: C12H25ClN2O3
Molecular weight: 280.79g/mol
Appearance: white crystalline solid
Melting point: 163-165°C
Use:
(2S,4R)-acid methyl ester hydrochloride are commonly used as intermediates in drug synthesis, mainly used in the synthesis of various drugs, such as anti-tumor drugs, antiviral drugs, etc.
Method:
(2S,4R)-acid methyl ester hydrochloride synthesis method is more complicated, roughly divided into the following steps:
1. (2S,4R)-4-aminopyrrolidine-2-carboxylic acid methyl ester is reacted with a tert-butanol acid protecting agent in an appropriate solvent to obtain (2S,4R)-4-Boc-aminopyrrolidine-2-carboxylic acid methyl ester.
2. The product obtained in step 1 is reacted with hydrochloric acid to generate (2S,4R)-4-Boc-aminopyrrolidine-2-carboxylic acid methyl ester hydrochloride.
3. Finally, the target product was obtained by crystallization.
Safety Information:
(2S,4R)-The acid methyl ester hydrochloride has limited safety information and should be used in strict compliance with laboratory safety practices to avoid contact with skin, eyes and mouth. In case of accidental contact, rinse immediately with plenty of water and seek medical help. Store in a closed container, away from fire and oxidizing agents. Detailed safety information can be found in the relevant chemical safety data sheets.
Nature:
Chemical name:(2S,4R)-acid methyl ester hydrochloride
Molecular formula: C12H25ClN2O3
Molecular weight: 280.79g/mol
Appearance: white crystalline solid
Melting point: 163-165°C
Use:
(2S,4R)-acid methyl ester hydrochloride are commonly used as intermediates in drug synthesis, mainly used in the synthesis of various drugs, such as anti-tumor drugs, antiviral drugs, etc.
Method:
(2S,4R)-acid methyl ester hydrochloride synthesis method is more complicated, roughly divided into the following steps:
1. (2S,4R)-4-aminopyrrolidine-2-carboxylic acid methyl ester is reacted with a tert-butanol acid protecting agent in an appropriate solvent to obtain (2S,4R)-4-Boc-aminopyrrolidine-2-carboxylic acid methyl ester.
2. The product obtained in step 1 is reacted with hydrochloric acid to generate (2S,4R)-4-Boc-aminopyrrolidine-2-carboxylic acid methyl ester hydrochloride.
3. Finally, the target product was obtained by crystallization.
Safety Information:
(2S,4R)-The acid methyl ester hydrochloride has limited safety information and should be used in strict compliance with laboratory safety practices to avoid contact with skin, eyes and mouth. In case of accidental contact, rinse immediately with plenty of water and seek medical help. Store in a closed container, away from fire and oxidizing agents. Detailed safety information can be found in the relevant chemical safety data sheets.
Last Update：2024-04-09 15:18:00
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Product Name: (2S,4R)-4-BOC-AMINO PYRROLIDINE-2-CARBOXYLIC ACID METHYLESTER-HCL Visit Supplier Webpage Request for quotation
CAS: 913742-54-8
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 913742-54-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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